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. 2019 Oct 13;2019:9480945. doi: 10.1155/2019/9480945

Figure 4.

Figure 4

Effects of QD on mRNA and protein expression of Th1/Th17-related cytokines and transcription factors in colon tissues of mice with DSS-induced colitis: (a) mRNA expression of IFN-γ, T-bet, IL-17A, and RORγt; (b) protein expression of IFN-γ, IL-17A/F, TNF-α, and IL-1β. Colitis was induced in all groups except the control group. QD and SASP were administered to mice from days 6 to 12. On day 13, the mice were sacrificed and mRNA expressions of IFN-γ, T-bet, IL-17A, and RORγt in the colon tissues were measured using RT-PCR. Protein expressions of IFN-γ, IL-17A/F, TNF-α, and IL-1β in the colon tissues were measured using ELISA. Data were expressed as mean ± SD (n = 6–8). #p < .05, ##p < .01, and ###p < .001, compared with the control group; ∗p < .05 and ∗∗p < .01, compared with the DSS model group.