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. 2019 Oct 13;2019:3248527. doi: 10.1155/2019/3248527

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Copyright © 2019 Mengsiyu Li et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of metformin on HFD/STZ-induced type 2 diabetic rats. Diabetes was induced in Wistar rats and then administered with or without metformin. At the end of the experiment, rats were fasted for 16 hours. OGTT was performed, and blood glucose (a) and serum insulin (b) at 0, 30, 60, 90, and 120 minutes were recorded. Data are mean ± SEM. ^∗Mean is significantly different compared with that of the CON group. ^#Mean is significantly different compared with that of the DM group (^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.001; ^#p < 0.05; ^##p < 0.01).