Table 6.
Combination of the top 10 ranked features from the best ordinal classifiers using SVM, RF, and PLR
| Measure | Region | Rank in SVM classifier | Rank in RF classifier | Rank in PLR classifier | Average rank |
|---|---|---|---|---|---|
| Mean FA (dMRI) | Left medial orbitofrontal | 1(10.54) | 2(4.08) | 2(5.06) | 1.67 |
| Mean FA (dMRI) | Right cuneus | 5(13.82) | 3(8.94) | 6(7.74) | 4.67 |
| Mean FA (dMRI) | Left lateral orbitofrontal | 3(12.42) | 6(12.05) | 12(14.89) | 7 |
| Gray matter volume asymmetry (sMRI) | Pericalcarine | 4(13.76) | 22(22.61) | 1(4.87) | 9 |
| Gray matter volume asymmetry (sMRI) | Precentral | 8(14.34) | 5(11.94) | 19(19.13) | 10.67 |
| Mean FA (dMRI) | Right rostral anterior cingulate | 7(14.32) | 20(22.42) | 7(8.21) | 11.33 |
| Mean FA (dMRI) | Right lingual | 9(15.56) | 7(13.00) | 20(19.31) | 12 |
| Gray matter volume asymmetry (sMRI) | Pars triangularis | 11(16.60) | 21(22.45) | 4(6.90) | 12 |
| Gray matter volume (sMRI) | Left pars orbitalis | 21(21.02) | 15(21.58) | 3(5.32) | 13 |
| Mean FA (dMRI) | Right entorhinal | 19(20.50) | 18(21.94) | 5(7.08) | 14 |
| Gray matter volume (sMRI) | Inferior temporal | 10(16.28) | 14(20.59) | 21(21.43) | 15 |
| Gray matter volume (sMRI) | Right pars triangularis | 6(14.06) | 23(22.85) | 17(18.18) | 15.33 |
| Mean FA (dMRI) | Left insula | 12(16.60) | 10(17.77) | 28(26.43) | 16.67 |
| Age | Age | 16(17.64) | 1(3.64) | 33(29.42) | 16.67 |
| Mean FA (dMRI) | Right caudal anterior cingulate | 2(10.98) | 36(24.98) | 16(17.18) | 18 |
| Gray matter volume asymmetry (sMRI) | Lingual | 14(17.40) | 33(24.57) | 9(12.00) | 18.67 |
| Mean FA (dMRI) | Left lateral occipital | 23(21.24) | 24(22.95) | 10(12.66) | 19 |
| Cortical thickness (sMRI) | Left hemisphere (average) | 15(17.62) | 9(14.11) | 38(32.09) | 20.67 |
| Gray matter volume (sMRI) | Right choroid plexus | 20(20.92) | 8(13.52) | 35(29.91) | 21 |
| Volume asymmetry (sMRI) | Cerebellum | 28(23.04) | 28(23.73) | 8(11.77) | 21.33 |
| Cortical thickness | Right hemisphere (average) | 34(24.64) | 4(9.55) | 36(30.32) | 24.67 |
MDD = major depressive disorder; HC = healthy controls; PLR = penalized logistic regression model with elastic net penalty; SVM = support vector machine; RF = random forest.
Notes. Numbers in the parentheses are the average rank from 10 repeated fivefold cross‐validation. Average rank refers to the mean rank across the three algorithms.