TABLE 1.

Summary of Studies Evaluating HuR as a Predictive Marker for Pancreatic Ductal Adenocarcinoma in the Adjuvant Setting

First Author	Year	Patient Population	No. Samples	Therapy	Findings
Costantino et al¹³	2009	TJUH	40	GEM ±Xeloda ± XRT	High cHuR: negative prognostic marker (OS HR 7.34, CI 2.05–26.22, p = 0.0022)
Richards et al¹²	2010	TJUH	53	GEM (n = 24)	High cHuR: negative prognostic marker (OS HR 2.84, CI 1.04–7.74, P = 0.04)
				No adjuvant therapy or follow-up (n = 21)	High cHuR: higher AJCC T stage (P = 0.005)
McAllister et al¹⁴	2014	RTOG9704	165	GEM + XRT (n = 76)	cHuR: no prognostic or predictive value
				5-FU + XRT (n = 89)
This study	2016	ESPAC-3	379	GEM (n = 193) 5-FU (n = 186)	High cHuR: positive predictive marker for 5-FU (DFS HR 0.51, CI 0.3–0.85, P = 0.01)
				5-FU (n = 186)