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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Mol Neurobiol. 2019 May 19;56(11):7719–7730. doi: 10.1007/s12035-019-1637-8

Figure 7:

Figure 7:

Synergistic interaction between CBN and THC, but not CBD and THC. Increasing concentrations of CBD or CBN and THC were added to 96 well tissue culture dishes perpendicular to each other. Sufficient glutamate was added to kill 90% of the cells in the absence of cannabinoids. The percent survival in each well is then plotted against the concentrations of the two compounds. The colors are consistent for each concentration of THC (0, blue; 0.1 μM, red; 0.2 μM, green). Higher concentrations of CBD were used than CBN. The arrows indicate conditions of maximum synergy in the case of CBN vs THC. There was only an additive effect of CBD with THC.