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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Contemp Clin Trials. 2019 Aug 26;85:105832. doi: 10.1016/j.cct.2019.105832

Table 3.

Cognitive Tests

Task Format Session Expected Domain(s) Baseline 6-months 12-months
Synonym and Antonym –VCAP battery*38 Computerized 1 Language
Montreal Cognitive Assessment39 (MOCA) Verbal; paper/pencil 1 General cognition
Trail Making A40 Paper-pencil 1 Processing Speed
Trail Making B40 Paper-pencil 1 Executive Function
Hopkins Verbal Learning Test34 (HVLT) Verbal 1 Verbal memory
Letter Fluency41 Verbal 1 Executive Function/Language
Category Fluency42 Verbal 1 Executive Function/Language
Brief Visuospatial Memory Test-Revised43 (BVMT) Paper-pencil 1 Visuospatial Memory
Wechsler Test of Adult Reading44 Verbal 1 Crystallized Intelligence
Digit Symbol Substitution Test44 Paper-pencil 1 Processing speed
Boston Naming45 Verbal 1 Language
Logical Memory – VCAP battery46 Computerized 2 Episodic Memory
Spatial Relations – VCAP battery47 Computerized 2 Visual-spatial
Paired Associates – VCAP battery48 Computerized 2 Episodic Memory
Matrix Reasoning – VCAP battery49 Computerized 2 Fluid Reasoning
Dimensional Card Sort Task – NIH Toolbox50 Computerized 2 Executive Function
List Sort Working Memory – NIH Toolbox50 Computerized 2 Working Memory
Picture Sequence – NIH Toolbox50 Computerized 2 Working Memory
Flanker – NIH Toolbox50 Computerized 2 Executive Function
Spatial Working Memory51 Computerized 2 Working Memory
Cohen’s Relational Memory52 Computerized 2 Relational/episodic Memory
Stroop Task Computerized 2 Executive Function
Task-switching Computerized 2 Executive Function
Iowa Gambling Task53 Computerized 2 Reward/Learning
Letter Comparison (VCAP)54 Paper-pencil 2 Processing speed
*

VCAP Synonym/Antonym is not used for adjudication but is administered at cognitive session 1.