Figure 5.

Changes in 11p13 gene expression with VPR‐mediated activation of promoters and cis‐elements in 16HBE14o‐ cells. VPR‐mediated activation of ELF5 promoter, EHF promoter and DHS at 11p13. EHF intron 6 encompasses Ca11.1058 and Ca11.1327. Error bars are SEM, n = 3. ****P < .0001, ***P < .001, **P < .01, *P < .05, ns = not significant by an unpaired Student's t test. † P < .0001 – statistically significant, but not biologically significant due to low expression levels. Inset panel shows ELF5, EHF and APIP gene expression for 16HBE14o‐ cells. Error bars are SEM, n = 3