Table 4.
Subgroup analyses of healing rates of peptic ulcers
Comparison |
Healing rate (%) |
Heterogeneity |
OR | 95%CI | P value | ||
Allicin group | Control | I2 (%) | P value | ||||
Allicin + PTT vs PTT[15-18,20] (ITT) | 80.32 | 68.29 | 0 | 0.527 | 2.14 | 1.39-3.29 | 0.001 |
Allicin + PTT vs PTT[15-18,20] (PP) | 80.65 | 68.57 | 0 | 0.513 | 1.93 | 1.25-2.96 | 0.003 |
Allicin-PPI-B-T-C vs PPI-B-T-C[21,22] (ITT/PP) | 95.51 | 87.82 | 22.924 | 0.255 | 2.83 | 1.13-7.10 | 0.026 |
Allicin-PPI-Am-F vs PPI-Am-F[15,18,20] (ITT/PP) | 83.26 | 65.00 | 0 | 0.660 | 1.90 | 1.18-3.06 | 0.002 |
PPI: Proton pump inhibitor; PTT: Proton pump inhibitor triple therapy; Am: Amoxicillin; F: Furazolidone; C: Clarithromycin; T: Tinidazole; B: Bismuth potassium citrate tablets; ITT: Intent-to-treat analysis; PP: Pre-protocol analysis; OR: Odds ratio; CI: Confidence interval.