Figure 5.

S1R influences many downstream targets in ferroptosis. A‐B, Indicated HCC cells were treated with erastin (10 μmol/L) or sorafenib (5 μmol/L) for 24 h. The mRNA levels of indicated genes were assayed (n = 3, *P < .05 vs control shRNA group). C, Indicated HCC cells were treated with erastin (10 μmol/L) or sorafenib (5 μmol/L) for 24 h and the protein expression of indicated genes were assayed using Western blot analysis