Table 3.

Treatment Outcomes of ESD.

ESD result per patient				PPI group 71 patients		VPZ group 59 patients		p
Curability, n (%)		Curative		54 (76)		53 (90)		0.04
		Noncurative		17 (24)		6 (10)
Perforation during ESD, n (%)				2 (2.8)		1 (1.6)		0.67
Ulcer protection		None		51 (72)		43 (73)		0.89
		Clip closure		10 (14)		15 (25)		0.1
		PGA		10 (14)		1 (2)		0.01
Hb drop after ESD, g/dL (average, range)				0.9 (-2.5-7.9)		0.95 (-2.6-9.1)		0.8
Hemostasis during second-look EGD, n (%)				9 (13)		11 (19)		0.34
Overall delayed bleeding after ESD				13 events (18%) in 9 patients		18 events (31%) in 17 patients		0.10
Delayed bleeding after 2 days of ESD, n (%)				12 (17)		8 (14)		0.59
Blood transfusion, n (%)				2 (2.8)		3 (5)		0.2

PGA: polyglycolic acid sheet, PPI: proton-pump inhibitor, VPZ: vonoprazan, EGD: esophagogastroduodenoscopy, ESD: endoscopic submucosal dissection, Hb: hemoglobin