Appendix B.

Sensitivity analysis comparing direct and indirect effects of HIV-related stigma on viral suppression among two samples of African-American women living with HIV enrolled in the Unity Study, differing by viral load collection period

	Primary sample (8-week viral load)		Sensitivity sample (24-week viral load)
	N = 100		N = 184
	β	(95% CI)	β	(95% CI)
Primary model*
Total effect (difference in log-odds)	−0.069	(−0.117, −0.021)	−0.052	(−0.084, −0.020)
Direct effect	−0.085	(−0.145, −0.025)	−0.043	(−0.082, −0.004)
Indirect effects
Stigma > depression > nonadherence > viral suppression	−0.006	(−0.045, 0.029)	−0.003	(−0.010, 0.002)
Stigma > depression > viral suppression	0.010	(−0.046, 0.054)	0.010	(−0.037, 0.014)
Stigma > nonadherence > viral suppression	0.002	(−0.087, 0.051)	0.001	(−0.012, 0.010)
Secondary model**
Total effect (difference in log-odds)	−0.096	(−0.016, −0.032)	−0.056	(−0.089, −0.022)
Direct effect	−0.238	(−0.385, −0.091)	−0.052	(−0.092, −0.011)
Indirect effects
Stigma > depression > nonadherence > viral suppression	−0.010	(−0.072, 0.054)	−0.002	(−0.011, 0.003)
Stigma > depression > viral suppression	0.064	(−0.140, 0.206)	0.006	(−0.034, 0.021)
Stigma > nonadherence > viral suppression	0.009	(−0.105, 0.107)	0.001	(−0.012, 0.011)

^*Adjusted for treatment, site, age, education, time living with HIV

^**Adjusted for treatment, site, age, education, time living with HIV, alcohol use severity