Date	Event	Description
19 March 2019	New citation required but conclusions have not changed	This is the fourth update of the original rotavirus vaccines review (Soares‐Weiser 2004). This review concerns vaccines that have been prequalified for global use by the WHO (WHO 2018). In the previous versions of this review we included any rotavirus vaccine in use.
19 March 2019	New search has been performed	We amended the protocol to include only vaccines prequalified for use by the World Health Organization (WHO). We included 14 new studies from the April 2018 search, including four studies on a new vaccine (Rotavac). Nicholas Henschke joined the author team.
10 May 2012	New search has been performed	No new trials were identified from the updated May 2012 search.
10 May 2012	New citation required but conclusions have not changed	Review updated to incorporate different country mortality strata and outcomes changed to reflect the different rotavirus vaccines’ efficacy and safety in countries with different mortality rates.
8 January 2012	New search has been performed	Review updated to include nine trials identified in a new literature search, which was conducted in October 2011 (MEDLINE via PubMed) and June 2011 (other databases).
11 November 2011	New citation required but conclusions have not changed	Hanna Bergman and Sukkrti Nagpal joined the author team.
10 May 2010	Amended	Minor typographical errors corrected.
2 February 2010	New citation required and conclusions have changed	A new search on 2 February 2010 identified 9 new potentially relevant studies. We independently assessed these studies and incorporated data from the eligible trials into the review.
21 July 2009	New search has been performed	The original rotavirus vaccines review (Soares‐Weiser 2004) was split into two reviews: rotavirus vaccines in use (this review); and other rotavirus vaccines, including those no longer in use or in development (Soares‐Weiser 2004). This involved a new search, revised inclusion criteria, updated review methods. All data from those trials also included in the original review were re‐extracted. New authors joined the review team for this review.