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. 2019 Sep 8;294(43):15836–15849. doi: 10.1074/jbc.RA119.010564

Figure 1.

Figure 1.

Silencing myeloid Acat1 rather than silencing Acat1 globally extends the life span of modified Paigen diet–fed ApoE−/− mice. A, body weights of male ApoE−/−, ApoE−/−/Acat1−M/−M, and ApoE−/−/Acat1−/− mice fed a modified Paigen diet for 20 weeks. B, survival curves of ApoE−/−, ApoE−/−/Acat1−M/−M, and ApoE−/−/Acat1−/− mice.