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. 2019 Sep 8;294(43):15836–15849. doi: 10.1074/jbc.RA119.010564

Figure 6.

Figure 6.

Blocking ACAT1 ameliorates AcLDL induced iNOS and COX2 expressions in RAW macrophages. RAW macrophages were treated without or with K604 at 0.5 μm for 18 h and then treated without or with 100 μg/ml of AcLDL for 24 h. A and C, Western blotting analysis of COX2 and iNOS protein expression. B and D, densitometry analysis of COX2 (B) and iNOS (D) protein expression. E, mRNA levels of pro-inflammatory response genes. The data are reported as means ± S.E. *, p ≤ 0.05; **, p ≤ 0.01.