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. 2019 Oct 28;20:523. doi: 10.1186/s12859-019-3137-2

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Example of orthologs that may be missed by full-length approaches because of their domain architecture, but not by domain-based orthology inference. Orthologous domains are marked with double arrows. Identifiers are UniProt accessions and Pfam domains (shown as coloured boxes) respectively