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. 2019 Oct 28;20:391. doi: 10.1186/s12882-019-1549-x

Table 3.

The difference of baseline parameters between favorable and unfavorable renal outcome at 6 months

Favorable renal outcome
(n = 53)
Unfavorable renal outcome
(n = 70)
P value
Plasma cf-mtDNA (GE/mL) 441.1 ± 525.6 370.6 ± 641.9 0.538
Plasma cf-nDNA (GE/mL) 760.9 ± 732.9 554.1 ± 850.9 0.184
Urine cf-mtDNA (GE/mL) 0.489 ± 0.751 3.745 ± 12.197 0.027*
Urine cf-nDNA (GE/mL) 1.764 ± 2.388 15.119 ± 40.791 0.009*
MCN (per cell) 87.21 ± 69.40 101.55 ± 95.75 0.356
Urine 8-OH dG/Cr 3.62 ± 2.44 4.03 ± 2.44 0.346
NGAL (ng/mL) 585.24 ± 251.62 780.85 ± 391.39 0.032*

*P < 0.05, Student’s test

MCN, mitochondrial copy number; NGAL, neutrophil gelatinase-associated lipocalin; 8-OH dG, 8-hydroxy-2-deoxyguanosine; cf-mtDNA, cell-free mitochondrial DNA; cf-nDNA, cell-free nuclear DNA; GE/mL, genome equivalents /mL

Favorable renal outcome indicated eGFR at 6 months minus baseline eGFR> = 0; unfavorable renal outcome indicated eGFR at 6 months minus baseline eGFR <0