Table 1.
Metabolic data of mice at the end of the experiment (mean ± SD).
| BW(g) | KW(mg) | KW/BW (mg/g) | BG(mmol/L) | SCr(mg/dL) | 24UTP(mg) | |
|---|---|---|---|---|---|---|
| Control(n = 8) | 23.98 ± 2.05 | 320.1 ± 55.1 | 13.35 ± 2.3 | 6.12 ± 1.06 | 0.52 ± 0.04 | 0.60 ± 0.20 |
| DN(n = 8) | 15.55 ± 0.56* | 345.2 ± 45.5 | 22.20 ± 2.93* | 25.61 ± 3.12* | 0.56 ± 0.04 | 4.51 ± 0.45* |
| HD(n = 8) | 19.52 ± 1.65# | 322.7 ± 43.6 | 16.53 ± 2.23# | 20.45 ± 3.56# | 0.57 ± 0.03 | 1.56 ± 0.52# |
| LV-vector(n = 8) | 19.98 ± 1.55 | 325.8 ± 41.1 | 16.31 ± 2.06 | 21.12 ± 3.41 | 0.53 ± 0.04 | 1.54 ± 0.41 |
| LV-LOC498759 (n = 8) | 17.12 ± 1.14& | 335.7 ± 43.9 | 19.61 ± 2.56& | 22.23 ± 3.15& | 0.55 ± 0.03 | 2.54 ± 0.52& |
BW, body weight; KW, kidney weight; KW/BW, kidney weight-to-body weight ratio; BG, blood glucose; SCr, serum creatinine; 24UTP, 24 h-urine total protein; *p < 0.05 vs. control; #p < 0.05 vs. DN; &p < 0.05 vs. HD+LV-vector.