Figure 16.

Score plot of ChemGPS-NP analysis of 94 fragments (1–22, 24–95) in this manuscript. PC1 (molecular size) versus PC2 (molecular aromaticity) versus PC3 (molecular lipophilicity) for sets of 10 fragments from chemical disassembly of larger natural products (1–10) (red), five fragments from chemical modification of small natural products (11–15) (blue), seven fragments from pseudo natural products (16–22) (magenta), 13 fragments from a low MW natural product library (24–36) (green), five fragments from other libraries (37–41) (cyan), 42 fragment hits against parasitic diseases (42–83) (dark yellow) and 12 natural product fragment hits against malaria (84–95) (orange).