TABLE 1.

Patient Characteristics. S: surgery, C: chemotherapy, RT: radiation therapy, AHCR: autologous hematopoietic cell rescue, DT: drug trial, AT: alternative therapy; Complete response (CR), Partial response (PR), No response (NR) or stable disease, Progressive disease (PD).

Age at Diagnosis	Sex	Diagnosis	Therapy prior to Thiotepa	Disease Status upon Enrollment	No. of Thiotepa Courses
40.1	Female	Anaplastic Astrocytoma	S, RT, C	PD	2
18	Male	Anaplastic Astrocytoma	S, C, RT	PR1	1
13.9	Male	Anaplastic Astrocytoma (Bithalamic)	RT	PR1	1
12.8	Male	Anaplastic JPA	S, RT	PR3	1
36	Male	Anaplastic Oligodendroglioma	RT, C, S	PD	2
2.1	Male	AT/RT	S, C	NR1	1
0.1	Male	AT/RT	S, C, DT, RT	PD	2
1	Female	Choroid Plexus Carcinoma	S,DT	PD	2
8.5	Male	CNS-Germ Cell Tumor	C	PD	2
9.1	Male	CNS-Germ Cell Tumor	C	PR1	2
30.7	Male	CNS-Germ Cell Tumor	C, RT	PR1	2
8.5	Male	CNS-Germ Cell Tumor	DT, RT	PD	2
19.7	Male	CNS-Germ Cell Tumor	AT, C, S	PD	1
5.4	Female	Ependymoma	S, C, RT	PD	2
7.4	Male	Ependymoma	S, RT, C	PD	2
3.1	Female	Ependymoma	S, RT, C	PR2	1
1.7	Male	Ependymoma	S, DT, RT	PD	2
15	Male	Ewing Sarcoma	S, C, DT	NR1	1
17.9	Male	Ewing Sarcoma	C, S, RT, DT	PD	2
7.6	Male	GBM	S, RT	PR1	1
28.5	Female	Leiomyosarcoma	S, RT, C	NR1	1
3.5	Male	Medulloblastoma	C	NR2	1
5.5	Male	Medulloblastoma	S, C, RT	PR1	1
4.3	Male	Medulloblastoma	C, RT	PD	1
36.3	Male	Medulloblastoma	S, C, RT	PD	2
6	Male	Medulloblastoma	S, RT, C	NR1	2
30.4	Male	Medulloblastoma	S, RT, C	PR1	2
6	Female	Medulloblastoma	S, RT, C	PR2	2
3	Female	Medulloblastoma	S, C, RT	PD	2
4	Male	Medulloblastoma	S, C, AT	PD	2
9.2	Male	Medulloblastoma	S, RT, C	NR3	2
7.8	Male	Medulloblastoma	S, RT, C	PR1	2
0.7	Female	Medulloblastoma	S, C	PR1	2
8.3	Male	Medulloblastoma	S, RT, C	PD	1
3.2	Male	Medulloblastoma	S, RT, C, AHCR	PD	2
18	Male	Medulloblastoma	S, C, RS, AHCR	PD	2
8.8	Male	Medulloblastoma	S, C, RT	PR2	1
34	Male	Medulloblastoma	S, RT, C	PD	2
24.6	Male	Medulloblastoma	S, C, RT	PR1	2
3.3	Female	Neuroblastoma	C, S, DT, AHCR	NR1	1
5.5	Male	Neuroblastoma	S, C, RT, DT	NR2	1
4.1	Male	Neuroblastoma	C, RT, S, AHCR, DT	NR1	2
6.1	Female	Neuroblastoma	C, S, RT, AT	NR1	2
5	Male	Neuroblastoma	S, C, AHCR, DT, AT	PR1	1
6.5	Male	Osteosarcoma	RT, C	PR1	1
39.8	Female	Pineoblastoma	S, C, RT	PD	2
15	Female	Pineoblastoma	RT, C	NR1	2
15.5	Female	Pineoblastoma	S, C, RT	PR1	1
0.4	Female	Pineoblastoma	C	PD	2
1.4	Male	Pineoblastoma	C	PD	1
36.2	Female	Pineoblastoma	S, C, RT	PD	2
9	Male	PNET	RT, C	NR1	2
1.2	Male	Retinoblastoma	S, RT, C	PR1	2
4.3	Male	Retinoblastoma	C, S, RT	NR1	2
1.5	Female	Retinoblastoma	S, C	PR1	2
4	Female	Rhabdomyosarcoma (Orbital)	C, S	PD	2
26	Female	Undifferentiated Carcinoma	RT, C	PR2	2
35.5	Male	Wilms Tumor	C, S, RT	NR2	2