Skip to main content
. Author manuscript; available in PMC: 2019 Oct 28.
Published in final edited form as: Mod Pathol. 2014 Sep 5;28(2):187–200. doi: 10.1038/modpathol.2014.109

FIGURE 4: Immunohistochemical expression patterns of neurofibromin,p16 and EGFR among malignant peripheral nerve sheath tumors and cellular schwannomas.

FIGURE 4:

A: Neurofibromin stain is retained diffusely in cellular schwannoma; B: Neurofibromin is lost in tumor cells in malignant peripheral nerve sheath tumor, and is retained in vasculature and inflammatory cells; C: p16 stain is diffusely positive in cellular schwannoma; D: p16 expression is lost in malignant peripheral nerve sheath tumor, and is retained in vasculature; E: EGFR stain is negative in cellular schwannoma; F: Diffuse EGFR expression in malignant peripheral nerve sheath tumor.