Figure 4:

PARGi decreases colony formation in PDAC cells in combination with oxaliplatin. (A) MIA PaCa-2 and (B) PANC-1 cell lines were treated with increasing doses of PDDX-001 (µM) alone and in combination with oxaliplatin (oxali) or olaparib (olap) and resulting colonies were fixed and stained with crystal violet solution. Representative images with graphs of relative colonies are shown. Mean ±SEM, n=3. ***P=0.0001 to 0.001, **P=0.001 to 0.01, *P=0.01 to 0.05, n.s= non-significant using two-sample t-tests.