Fig 1. The ECM exhibits diversity in vivo.
(A) Second harmonic imaging of collagen (orange) in various tissues from a PDGFR nuclear labelled mouse. PDGFR positive nuclei (cyan) indicates fibroblast density. (B) Each matrix is characterized on a starplot below the image according to long-range alignment (LRA), short-range alignment (SRA), percentage of high density matrix (HDM), curvature (Curv) and fractal dimension (Frac). Scale bars represent 100μm.