Fig 2. Lymphocyte differentiation by frequency.

A-D, Frequencies of CD3⁺, CD4⁺, and CD8⁺ Naive (N), Central Memory (CM), Effector Memory (EM), and Terminally Differentiated (TD) T Cells in control subjects (n = 20), patients with infection (n = 19), and patients with sepsis (n = 32). Data represented as median with interquartile range. E-F, Frequencies of CD4⁺ Naïve and Effector Memory T Cells at admission (n = 32), at 7 days (n = 20), 14 days (n = 14) and 21 days (n = 15). SE = standard error of the mean. NS = non significant, N/A = Not applicable. All comparisons with admission values, with Bonferroni correction for multiple comparisons. (# = p<0.05;* = p<0.01;** = p<0.001; *** = p<0.0001).