A; HLA-DR+ monocytes expressing IL12. B; T Lymphocytes expressing IL12R. C; HLA-DR+ monocytes expressing IL23. D; T Lymphocytes expressing IL23R. E; Monocytes expressing HLA-DR+. F; T lymphocytes expressing IL23R by differentiation status, ie Naive (N), Central Memory (CM), Effector Memory (EM), and Terminally Differentiated (TD). Control subjects (n = 20 in T cell group, 10 in monocyte group), patients with infection (n = 19 in T cell group, 10 in monocyte group), and patients with sepsis (n = 32 in T cell group, 10 in monocyte group). Monocytes are unstimulated (medium) or stimulated with lipopolysaccharide (LPS) or phorbol myristate acetate (PMA) and ionomycin. Data represented as median with interquartile range. (# = p<0.05;* = p<0.01;** = p<0.001; *** = p<0.0001).