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. 2019 Oct 28;14(10):e0224276. doi: 10.1371/journal.pone.0224276

Fig 5. Frequency of RORγt and T-bet expression in CD3+, CD3+CD4+, CD3+CD8+ lymphocytes.

Fig 5

A-G. Expression of transcription factors RORγt and T-bet in CD3+, CD3+CD4+, and CD3+CD8+ Lymphocytes and in CD3+ Naive (N), Central Memory (CM), Effector Memory (EM), and Terminally Differentiated (TD) Cells. Co-expression of T-bet in CD3+, CD3+CD4+, and CD3+CD8+ lymphocytes was also analysed in 4E-G where RORγ(t)-T-bet+ only expressed T-bet+; RORγ(t)+T-bet+ co-expressed the two transcription factors; RORγ(t)+T-Bet- only expresed RORγ(t)+; and RORγ(t)-T-Bet- denoted cells that expressed neither. n, number of patients. Data represented as median with interquartile range. (# = p<0.05;* = p<0.01;** = p<0.001; *** = p<0.0001).