Table 1.

Summary of demographic, smoking, spirometry and model inclusion information.

Age (yrs)	Sex	FEV1 (% predicted)	FEV1/FVC	Pack-years	Smoking status	# AE-COPD during study	ICS use (Y/N)	Use in modelsa
74	Female	51	0.5	50	Former	3	Yes	Allb
77	Male	28	0.5	50	Former	1	Yes	All
69	Male	14	0.34	98	Former	3	Yes	Allc
59	Male	47	0.63	18	Former	1	Yes	All
72	Male	36	0.55	39	Former	2	Yes	All
58	Male	26	0.44	25	Former	1	Yes	Serum
67	Male	52	0.61	108	Current	1	Yes	All
66	Male	29	0.43	40	Current	1	No	All
67	Male	20	0.46	84	Current	1	Yes	Serum
72	Male	31	0.25	120	Current	1	Yes	Serum
66	Female	33	0.35	104	Current	1	Yes	Serum
67.9d	9/2	33.4	0.5	66.9	6/5	1.5	10/1

^aExcept where indicated, shows if any paired stable and exacerbation measurement from that patient was used in a data-driven model. “All” indicates at least one stable or AE-COPD measurement from that patient was used in all three data-driven models, and “Serum” means at least one paired stable and AE-COPD measurement from that patient was used only in the serum model

^bOnly an exacerbation measurement was used from this patient in the data-driven model based on serum, sputum and flow data

^cOnly a stable measurement was used from this patient in the data-driven model based on serum, sputum and flow data

^dData are presented as averages, except in the cases of gender (Male/Female), Smoking status (Former/Current) and ICS use (Yes/No)