Figure 3.
LNP biodistribution varies within newly reported cellular subsets. (a) FACS markers for two Kupffer and two endothelial cells subsets. (b) Kupffer cells subsets and reported phenotype. (c) Endothelial cell subsets and reported intra-hepatic location. (d) DNA delivery as mediated by cKK-E12 to Kupffer cell subsets. (e) DNA delivery as mediated by MC3 to Kupffer cell subsets. (f) DNA delivery as mediated by cKK-E12 to endothelial cell subsets. (g) DNA delivery as mediated by MC3 to endothelial cell subsets. ***p < 0.001, ****p < 0.0001, Two-Tail T-Test. Error bars are reported as standard error.
