Figure 7.
(a) Normalized cell traction force in trailing region and speed as function of time of typical MC3T3 cell underwent forward migration with guiding pattern. Arrows indicate moments when trailing region was released, which were at 29 and 59 min, respectively. Durations of traction force to buildup and drop are indicated as tI and tD, respectively. (b) Normalized traction force in trailing region while cell shape contracted and elongated during migration with and without guiding pattern. (c) Durations of force to increase and decrease during migration with and without guiding pattern. Number of cells during guided and non-guided migration is 29 and 23, respectively.