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Inhibitors and their treatment conditions for achieving endocytic inhibition by defined working mechanism.
| Endocytic inhibitors | Working mechanism | Working concentration | Incubation time (hours) |
|---|---|---|---|
| NaN3/DOG (37°C) | ATP depletion | 10 mM/50 mM | 1 |
| NaN3/DOG (4°C) | ATP depletion + slows down metabolism | 10 mM/50 mM | 1 |
| CPM | Inhibits clathrin mediated endocytosis | 28 nM | 1 |
| Nystatin | Inhibits lipid-raft mediated endocytosis | 180 nM | 1 |
| Dynasore | Inhibits dynamin-dependent endocytosis | 80 μM | 1 |
