Table 4.
Application of partitioning criteria to glycemic markers in age
| Case | Data for subgroup distributions | Lahti‐distances partitioning criteria | |||||||
|---|---|---|---|---|---|---|---|---|---|
| D (SD) | Conclusion for one end | ||||||||
| Subgroup1 (20‐39 y) | Subgroup2 (40‐59 y) | Subgroup3 (60‐79 y) | 1 vs 2 | 2 vs 3 | 1 vs 3 | 1 vs 2 | 2 vs 3 | 1 vs 3 | |
| GA (%) | |||||||||
| Lower limit | 10.29 | 10.38 | 10.22 | 0.108 | 0.178 | 0.084 | Nonpartitioning | Nonpartitioning | Nonpartitioning |
| Upper limit | 13.80 | 14.27 | 15.18 | 0.566 | 1.011 | 1.663 | Marginal | Partitioning | Partitioning |
| Mean±SD# | 11.98±0.83 | 12.20±0.90 | 12.41±0.99 | ||||||
| FA (μmol/L) | |||||||||
| Lower limit | 217.0 | 221.5 | 221.4 | 0.234 | 0.005 | 0.229 | Nonpartitioning | Nonpartitioning | Nonpartitioning |
| Upper limit | 298.0 | 301.5 | 301.4 | 0.182 | 0.005 | 0.177 | Nonpartitioning | Nonpartitioning | Nonpartitioning |
| Mean±SD* | 257.1±19.3 | 258.5±19.2 | 260.6±19.2 | ||||||
| 1,5‐AG (μmol/L) male | |||||||||
| Lower limit | 107.3 | 114.7 | 87 | 0.132 | 0.450 | 0.363 | Nonpartitioning | Marginal | Marginal |
| Upper limit | 347.6 | 378.5 | 372.5 | 0.552 | 0.098 | 0.445 | Marginal | Nonpartitioning | Marginal |
| Mean±SD# | 228.9±56.0 | 225.5±61.5 | 221.8±70.6 | ||||||
| Female | |||||||||
| Lower limit | 80.3 | 71.4 | 80.1 | 0.213 | 0.163 | 0.005 | Nonpartitioning | Nonpartitioning | Nonpartitioning |
| Upper limit | 242.9 | 295.9 | 346.8 | 1.271 | 0.951 | 2.492 | Partitioning | Partitioning | Partitioning |
| Mean±SD* | 156.8±41.7 | 174.0±53.5 | 213.0±70.6 | ||||||
Compared variables across three age groups: #P<.001, *P>.05. 1,5‐AG (μmol/L)≈6×1,5‐AG (μg/mL).
The ratio of the distance between reference limit of subgroups and the smaller SD of each subgroup, D. The results are compared with others using Lahti algorithm to judge the need for partitioning: Marginal (the subgroup reference limits at each end of the distribution between 0.25SD to 0.75SD); nonpartitioning, no need for partitioning (the subgroup reference limits at each end of the distribution <0.25SD); partitioning, need for partitioning (the subgroup reference limits at each end of the distribution >0.75SD).
SD, Standard deviations; 1,5‐AG, 1,5‐anhydroglucitol; GA, glycated albumin; FA, fructosamine; 1 VS 2, subgroup1 vs subgroup 2; 2 VS 3, subgroup2 vs subgroup3; 1 VS 3, subgroup1 vs subgroup3.