Table 5.

Gene mutation distribution among the patients

Gene	Overall (n = 168)	Normal (n = 118)	HPR (n = 50)	P value
CYP2C19*2	94	70 (74.47%)	24 (24.74%)	.234
CYP2C19*3	33	6 (18.18%)	27 (81.82%)	<.001
ABCB1 3435CT	109	81 (74.31%)	28 (25.69%)	.157

CYP2C19: cytochrome P450 family 2 subfamily C member 19; CYP2C19*2: rs4244285; CYP2C19*3: rs4986893; ABCB1: ATP binding cassette subfamily B member 1; ABCB1 3435CT: rs1045642. Bold value <.001 indicates that the gene mutation rate of patients with CYP2C19*3 was significantly higher than that in normal group.