Table 3.

Stratification analyses of rs12654812 association with nephrolithiasis risk

Subgroup	Case n = 830		Controls n = 711		P values	OR (95% CI)
	G/G	G/A + A/A	G/G	G/A + A/A
Age (years)
<50	270	187	252	151	.019	1.548 (1.075‐2.228)
≥50	224	149	197	111	.424	1.194 (0.773‐1.846)
Sex
Male	289	189	240	146	.065	1.399 (0.979‐1.998)
Female	205	147	209	116	.131	1.420 (0.901‐2.239)
BMI	n = 824		n = 616
≤24	331	223	214	128	.113	1.354 (0.930‐1.971)
>24	157	113	179	95	.077	1.451 (0.961‐2.193)
Smoking status	n = 798		n = 681
Ever	151	114	76	34	.018	1.929 (1.119‐3.327)
Never	322	211	361	210	.371	1.161 (0.837‐1.610)
Drinking status	n = 790		n = 431
Ever	164	146	154	82	.009	1.722 (1.146‐2.588)
Never	303	177	126	69	.631	1.100 (0.746‐1.620)
Crea (μmoI/L)	n = 826		n = 613
≤106	348	249	378	212	.006	1.535 (1.130‐2.084)
>106	142	87	12	11	.159	0.428 (0.131‐1.395)
UA (μmoI/L)	n = 826		n = 615
≤420	379	244	267	153	.117	1.302 (0.936‐1.812)
>420	111	92	125	70	.042	1.869 (1.024‐3.413)
BUN (mmol/L)	n = 769		n = 114
≤7.14	365	249	70	39	.191	1.379 (0.852‐2.231)
>7.14	89	66	2	3	.402	0.414 (0.052‐3.267)

P < .05 are marked in bold.

P adjusted for age, sex, BMI, smoking, drinking, and hypertension in logistic regression model (except stratified variables).