Table 3.
Clinical characteristics according to the genotypes of SNPs
| Genotypes | TG (mmol/L) | CT (mmol/L) | HDL‐C (mmol/L) | LDL‐C (mmol/L) | Glycemia (mmol/L) | BMI (kg/m2) | WC (cm) | HM (cm) | |
|---|---|---|---|---|---|---|---|---|---|
| 45T/G | TT | 0.79 [0.16‐14.3] | 4.92±0.99 | 1.16±0.35 | 3.31±0.80 | 5.74±1.99 | 27.8 [15.7‐48.2] | 94.68±13.82 | 104.66±11.97 |
| TG | 0.76 [0.2‐5.01] | 4.85±0.96 | 1.13±0.35 | 3.27±0.82 | 5.72±1.89 | 28 [16.3‐44.2] | 94.87±13.45 | 104.70±11.08 | |
| GG | 0.87 [0.35‐2.32] | 5.07±0.94 | 1.09±0.31 | 3.48±0.84 | 5.64±1.61 | 27.7 [19.1‐46.4] | 98.35±16.92 | 106.29±10.59 | |
| P | .408 | .265 | .220 | .281 | .932 | .576 | .154 | .589 | |
| 276G/T | GG | 0.76 [0.24‐14.7] | 4.94±1.00 | 1.16±0.34 | 3.36±0.81 | 5.79±2.17 | 28.7 [18.1‐48.2] | 96.22±14.9 | 106.05±11.72 |
| GT | 0.75 [0.16‐3.87] | 4.86±0.99 | 1.15±0.34 | 3.28±0.807 | 5.64±1.91 | 27.0 [16.3‐46.1] | 103.1±11.2 | 103.15±11.29 | |
| TT | 0.83 [0.19‐14.31] | 4.9±1.01 | 1.14±0.32 | 3.27±0.83 | 5.88±2 | 29.1 [17.1‐45.5] | 106.48±11.3 | 106.48±11.36 | |
| P | .041 | .514 | .771 | .369 | .290 | .010 | <.001 | <.001 | |
| 4522C/T | CC | 0.7 [0.2‐5.5] | 4.89±1.01 | 1.15±0.338 | 3.31±0.38 | 5.74±1.98 | 27.5 [15.7‐44.3] | 94.36±13.9 | 103.96±11.17 |
| CT | 0.82 [0.19‐14.31] | 4.97±0.96 | 1.13±0.337 | 3.36±0.786 | 5.74±2.06 | 29.1 [16.8‐48.2] | 96.69±14.2 | 106.29±11.96 | |
| TT | 0.68 [0.31‐3.5] | 4.97±0.87 | 1.23±0.35 | 3.17±0.805 | 5.49±1.41 | 29.1 [16.3‐39.4] | 92.07±3.55 | 102.79±10.03 | |
| P | .046 | .196 | .045 | .148 | .455 | .028 | .002 | .001 | |
| 395G/A | GG | 0.78 [0.19‐14.3] | 4.92±1.01 | 1.16±0.33 | 3.30±0.82 | 5.64±1.77 | 27.8 [16.3‐48.2] | 94.94±13.8 | 104.78±11.79 |
| GA | 0.76 [0.16‐5.57] | 4.89±1 | 1.16±0.36 | 3.31±0.84 | 5.71±1.92 | 27.6 [27.6‐46.8] | 94.57±14.9 | 104.32±11.75 | |
| AA | 0.84 [0.28‐3.5] | 4.84±1.04 | 1.108±0.37 | 3.31±0.86 | 5.85±2.03 | 28.4 [19.2‐41.6] | 96.19±13.3 | 106.05±12.38 | |
| P | .523 | .768 | .510 | .985 | .610 | .729 | .646 | .484 | |
| 420C/G | CC | 0.75 [0.2‐5.8] | 4.83±1.01 | 1.13±0.32 | 3.27±0.83 | 5.75±1.98 | 27.6 [17.4‐42.4] | 92.82±13.58 | 103.17±10.25 |
| CG | 0.86 [0.16‐14.7] | 4.99±0.99 | 1.16±0.36 | 3.34±0.8 | 5.84±1.98 | 30.2 [15.7‐46.1] | 98.74±14.23 | 107.406±12.18 | |
| GG | 0.72 [0.2‐3.52] | 4.76±0.95 | 1.15±0.32 | 3.21±0.79 | 5.59±2 | 26.7 [16.8‐48.2] | 91.77±0.56 | 103.48±10.94 | |
| P | <.001 | .002 | .665 | .111 | .189 | <.001 | <.001 | <.001 | |
|
LEP 2548G/A |
GG | 0.77 [0.16‐5.5] | 4.91±1.09 | 1.14±0.30 | 3.33±0.87 | 5.67±1.94 | 26.9 [16.8‐48.2] | 91.71±13.42 | 103.05±10.35 |
| GA | 0.76 [0.23‐14.3] | 4.89±0.97 | 1.15±0.34 | 3.30±0.82 | 5.71±1.88 | 27.8 [15.7‐46.8] | 94.99±14.54 | 104.29±11.77 | |
| AA | 0.24 [0.24‐5.82] | 4.89±0.94 | 3.27±0.75 | 3.27±0.75 | 5.63±1.72 | 29.36 [16.4‐44] | 96.35±0.43 | 106.32±11.90 | |
| P | .937 | .976 | .347 | .794 | .299 | <.001 | <.001 | .021 | |
|
LEPR Q223R |
GG | 0.78 [0.25‐5.57] | 4.90±0.97 | 1.16±0.33 | 3.29±0.79 | 5.67±1.97 | 27.9 [15.7‐48.2] | 95.42±14.9 | 105.02±11.42 |
| GA | 0.78 [0.16‐5.01] | 4.98±1.02 | 1.13±0.33 | 3.32±0.84 | 5.67±1.81 | 27.7 [17.4‐46.1] | 94.54±13.47 | 104.67±11.41 | |
| AA | 0.68 [0.2‐14.31] | 4.86±1 | 1.19±0.41 | 3.19±0.82 | 5.88±2.22 | 29.3 [17.6‐43.3] | 92.55±13.03 | 102.35±0.60 | |
| P | .492 | .945 | .346 | .470 | .663 | .246 | .151 | .098 | |
BMI, body mass index; TC, total cholesterol; TG, triglyceride; HDL‐C, high‐density lipoprotein‐cholesterol; LDL, low‐density lipoprotein‐cholesterol; WC, waist circumference; HM, hip measurement.
Mean±standard deviation or n (%).