Table 5.
Associations between ADIPOQ, LEP, LEPR, and RETN genotypes and the risk of obesity
| Polymorphisms | OR crude | CI | P | OR adjusteda | CI | P | |
|---|---|---|---|---|---|---|---|
| ADIPOQ |
45T/G GG+TG/TT |
0.943 | 0.721‐1.216 | .649 | 0.831 | 0.350‐1.975 | .675 |
|
4522C/T CT+TT/CC |
1.52 | 1.230‐1.994 | <.001 | 1.38 | 1.104‐9.252 | .037 | |
|
395G/A AA+GA/GG |
1.135 | 0.88‐1.44 | .312 | 1.994 | 0.354‐11.23 | .434 | |
|
276G/T TT+GT/GG |
0.603 | 0.467‐0.779 | <.001 | 0.608 | 0.465‐0.794 | <.001 | |
| RETN |
420C/G CG+GG/CC |
1.48 | 1.09‐2 | .011 | 2.18 | 1.59‐2.98 | <.001 |
| LEPR |
Q223R GA+AA/GG |
0.896 | 0.703‐1.142 | .376 | 1 | 0.995‐1.005 | .979 |
| LEP |
G2548A AA+GA/GG |
2.36 | 1.75‐3.18 | <.001 | 2.23 | 1.393‐12.73 | .034 |
The bold values are significant (P<.05).
a
After adjustments for age, smoking, gender, physical activity, and coffee consumption.