Table 3.
‐607G/T and ‐137G/C association with breast cancer susceptibility (Malignant vs Healthy)
| Mode | ‐607G/T | Malignant (%) | Healthy (%) | OR (95% CI) | P value | OR* (95% CI) | P* value | AIC | BIC |
|---|---|---|---|---|---|---|---|---|---|
| Condominant | T/T | 50 (29.6) | 41 (25.6) | 1.00 | 1.00 | 473 | 484.5 | ||
| G/T | 80 (47.3) | 80 (50) | 1.22 (0.73‐2.04) | .522 | 1.12 (0.65‐1.92) | .534 | |||
| G/G | 39 (23.1) | 39 (24.4) | 1.15 (0.63‐2.09) | .758 | 1.16 (0.62‐2.20) | .626 |
| Allele | Malignant (%) | Healthy (%) | Chi‐square test | P value |
|---|---|---|---|---|
| T | 187 (53) | 162 (51) | χ2 | |
| G | 169 (47) | 158 (49) | 0.244 | .621 |
| ‐137G/T | Malignant (%) | Healthy (%) | OR (95% CI) | P value | OR* (95% CI) | P* value | AIC | BIC | |
|---|---|---|---|---|---|---|---|---|---|
| Overdominant | C/C‐G/G | 122 (72.6) | 131 (81.9) | 1.00 | .063 | 1.00 | |||
| G/C | 46 (27.4) | 29 (18.1) | 0.61 (0.36‐1.03) | 0.54 (0.31‐0.93) | .025 | 424.8 | 436.2 |
| Allele | Malignant (%) | Healthy (%) | Chi‐square test | P value |
|---|---|---|---|---|
| C | 305 (86) | 289 (90) | χ2 | |
| G | 49 (14) | 31 (10) | 2.773 | .096 |
The odds ratios (OR) with their 95% confidence intervals (CI) were estimated by logistic regression models. The adjusted odds ratios (OR*) and P* were estimated by multiple logistic regression models, after adjusting age of first diagnosis. Best model according to the Akaike Information Criteria (AIC) and Bayesian Information Criteria (BIC).