Table 5.
Association between polymorphisms of the PPARγ gene and the susceptibility to sepsis
| SNP | Genotype | Sepsis group (n = 303) | Control group (n = 303) | OR (95% CI) | P value |
|---|---|---|---|---|---|
| rs2972164 | CC | 250 (82.51) | 266 (87.79) | 1 | |
| CT | 50 (16.50) | 35 (11.55) | 1.74 (1.05‐2.86) | .03 | |
| TT | 3 (0.99) | 2 (0.66) | 1.52 (0.24‐9.45) | .65 | |
| CC | 250 (82.51) | 266 (87.79) | 1 | ||
| CT+TT | 53 (17.49) | 37 (12.21) | 1.72 (1.06‐2.80) | .026 | |
| CC+CT | 300 (99.01) | 301 (99.34) | 1 | ||
| TT | 3 (0.99) | 2 (0.66) | 1.41 (0.23‐8.73) | .71 | |
| C allele | 550 (90.8) | 567 (93.6) | 1 | ||
| T allele | 56 (9.2) | 39 (6.4) | 1.64 (1.04‐2.58) | .033 | |
| rs1801282 | CC | 272 (89.77) | 257 (84.82) | 1 | |
| CG | 30 (9.90) | 46 (15.18) | 0.55 (0.33‐0.92) | .024 | |
| GG | 1 (0.33) | 0 (0.00) | ‐ | 1 | |
| CC | 272 (89.77) | 257 (84.82) | 1 | ||
| CG+GG | 31 (10.23) | 46 (15.18) | 0.57 (0.35‐0.95) | .03 | |
| CC+CG | 302 (99.67) | 303 (100.00) | 1 | ||
| GG | 1 (0.33) | 0 (0.00) | ‐ | .23 | |
| C allele | 574 (94.72) | 558 (92.08) | 1 | ||
| G allele | 32 (5.28) | 48 (7.92) | 0.62 (0.39‐1.01) | .055 |
Data shown as n (%).
Bold values meant values which were statistically significant.
CI, confidence interval; OR, odds ratio.