Table 6.
Association between polymorphisms of the PPARγ gene and organ dysfunction of sepsis
| SNP | Genotype | Mild (n = 238) | Severe (n = 65) | OR (95% CI) | P value |
|---|---|---|---|---|---|
| rs4135275 | AA | 71 (29.83) | 15 (23.08) | 1 | |
| AG | 130 (54.62) | 42 (64.62) | 2.66 (1.16‐6.09) | .038 | |
| GG | 37 (15.55) | 8 (12.31) | 1.18 (0.37‐3.71) | .78 | |
| AA | 71 (29.83) | 15 (23.08) | 1 | ||
| AG+GG | 167 (70.17) | 50 (76.92) | 2.21 (1.00‐4.85) | .042 | |
| AA+AG | 201 (84.45) | 57 (87.69) | 1 | ||
| GG | 37 (15.55) | 8 (12.31) | 0.65 (0.24‐1.75) | .38 | |
| A allele | 272 (57.14) | 72 (55.38) | 1 | ||
| G allele | 204 (42.86) | 58 (44.62) | 1.22 (0.76‐1.96) | .41 |
Data shown as n (%).
Bold values meant values which were statistically significant.
CI, confidence interval; OR, odds ratio.