Figure 3.

Hsa_circ_0000567 was downregulated in CRC tissues and CRC cell lines. (A) qRT‐PCR was performed to detect hsa_circ_0000567 expression in 102 paired CRC tissues and adjacent noncancerous tissues, and the results were presented as the fold change in CRC cancer tissues relative to the matched normal tissues. (B) The relative expression of hsa_circ_0000567 in 102 pairs of human CRC tissues (Cancer) and the adjacent noncancerous tissues (Normal) by qRT‐PCR analysis. (C) Hsa_circ_0000567 was decreased in 5 CRC cell lines (SW480, RKO, CACO2, SW620, and HCT116) compared with the normal colorectal epithelium cell line FHC by qRT‐PCR analysis. **P < .01, ****P < .0001