Table 3.
Comparison of ranges and median hematology values among children with various diseases in Tamale
| Analyte (unit) | Mal (N = 76) | Typ (N = 20) | SCD (N = 15) | Mal + Typ (N = 9) | Diarrhea (N = 30) | Reference | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Range | Median | Range | Median | Range | Median | Range | Median | Range | Median | Range | P a | |
| RBC (106/μL) | 1.31‐6.33 | 4.03 | 3.09‐5.91 | 4.65 | 4.00‐6.20 | 4.71 | 4.04‐5.82 | 4.44 | 1.91‐6.11 | 5.02 | 2.50‐5.50 | <.001 |
| Hb (g/dL) | 7.5‐12.1 L | 10.1 | 10.0‐17.2 | 12.9 | 9.5‐12.4 L | 11.4 | 8.2‐11.8 L | 10.2 | 7.9‐15.9 | 10.6 | 13.0‐18.0 | <.001 |
| HCT (%) | 13.1‐43.3 | 31.2 | 24.4‐51.0 | 35.9 | 28.3‐85.9 | 33.1 | 28.5‐44.9 | 32.1 | 7.6‐54.4 | 33. 5 | 26.0‐50.0 | .0519 |
| MCV (fL) | 51.3‐85.9 L | 69.6 | 56.9‐84.7 L | 80.1 | 22.5‐81.5 L | 72.9 | 56.7‐85.2 L | 78.4 | 54.4‐91. 5 | 72.8 | 86.0‐110.0 | .002 |
| MCH (pg) | 15.0‐34.5 | 25.7 | 17.6‐29.4 | 25.9 | 15.3‐25.6 L | 21.7 | 20.7‐32.5 | 25.2 | 14.8‐29.9 | 23.4 | 26.0‐36.0 | <.001 |
| MCHC (g/dL) | 25.4‐38.3 | 31.2 | 27.2‐38.0 | 31.7 | 123.0‐34.9 | 30.4 | 26.0‐35.0 | 31.8 | 22.3‐38.9 | 30.0 | 25.4‐37.6 | .279 |
| RDW_CV (%) | 12.40‐29.8 | 14.8 | 12.5‐24.5 | 15.8 | 14.2‐25.5 | 20.0 | 12.7‐22.4 | 18.7 | 12. 5‐27.9 | 20.8 | 11.0‐16.0 | <.001 |
| RDW_SD (fL) | 33.2‐66.0 | 43.8 | 34.5‐56.6 | 43.0 | 37.7‐60.8 | 43.6 | 36.1‐55.6 | 42.7 | 32.8‐62.8 | 46.6 | 37.0‐54.0 | .164 |
| WBC (10³/μL) | 2.40‐28.12 | 7.71 | 3.56‐20.30 | 7.21 | 2.07‐14.41 | 6.69 | 5.22‐15.72 | 7.38 | 2.76‐16.81 | 8.27 | 3.00‐15.00 | .358 |
| LYMP (%) | 3.8‐63.2 | 29.7 | 5.1‐55.3 | 41.7 | 11.3‐63.3 | 28.9 | 9.1‐55.6 | 28.1 | 14. 5‐62.2 | 33.7 | 20.0‐50.0 | .175 |
| LYMP# (10³/μL) | 0.5‐7.5 | 2.0 | 0.5‐5.1 | 2.4 | 1.2‐5.6 | 2.4 | 1.0‐6.3 | 2.3 | 0.7‐5.1 | 2.3 | 1.00‐3.70 | .579 |
| NEUT (%) | 19.7‐90.3 | 59.4 | 25.5‐89.9 | 42.8 | 21.9‐80.2 | 53.5 | 31.0‐79.9 | 63.5 | 19.7‐76.9 | 51.2 | 37.0‐72.0 | .131 |
| NEUT# (10³/μL) | 0.53‐11.34 | 4.59 | 1.11‐8.30 | 3.16 | 0.83‐11.55 | 3.82 | 1.93‐9.57 | 3.97 | 0.62‐9. 51 | 3. 43 | 1.50‐7.00 | .069 |
| MONO (%) | 1.7‐29.1 | 11.1 | 4.8‐18.0 | 11.4 | 7.1‐28.2 | 12.9 | 7.1‐15.2 | 11.2 | 5. 4‐27.7 | 13.2 | 0.0‐14.0 | .128 |
| MONO# (10³/μL) | 0.12‐3.55 | 0.8 | 0.38‐2.15 | 0.7 | 0.41‐1.88 | 1.0 | 0.57‐1.27 | 0.9 | 0.19‐3.45 | 0.9 | 0.00‐0.70 | .359 |
| EOS (%) | 0.0‐12.5 | 0.2 | 0.0‐10.3 | 0.8 | 0.0‐6.1 | 0.2 | 0.0‐1.6 | 0.2 | 0.0‐18.6 | 0.4 | 0.0‐6.0 | <.001 |
| EOS# (10³/μL) | 0.00‐0.63 | 0.01 | 0.00‐0.61 | 0.06 | 0.00‐0.42 | 0.03 | 0.00‐1.29 | 0.01 | 0.01‐0.18 | 0.05 | 0.00‐0.40 | .002 |
| BASO (%) | 0.0‐3.3 | 0.1 | 0.0‐0.5 | 0.1 | 0.0‐1.9 | 0.1 | 0.0‐0.7 | 0.1 | 0.0‐3. 4 | 0.1 | 0.0‐1.0 | .081 |
| BASO# (10³/μL) | 0.00‐0.71 | 0.01 | 0.00‐0.05 | 0.01 | 0.00‐0.11 | 0.01 | 0.00‐0.06 | 0.01 | 0.00‐1.49 | 0.01 | 0.00‐0.10 | .101 |
| PLT (10³/μL) | 21‐614 | 124 | 60‐766 | 296 | 51‐604 | 198 | 85‐508 | 171 | 6‐812 | 301 | 150‐400 | .001 |
| MPV (fL) | 9.3‐14.7 | 11.4 | 8.7‐14.0 | 10.8 | 9.5‐14.5 | 11.0 | 9.3‐14.5 | 11.1 | 9. 4‐13.7 | 11. 5 | 9.0‐13.0 | .426 |
| PDW (fL) | 9.0‐21.9 | 13.4 | 8.9‐18.4 | 12.2 | 9.9‐21.9 | 13.0 | 9.9‐21.9 | 13.1 | 9. 7‐20. 4 | 12. 5 | 9.0‐17.0 | .438 |
| PCT (%) | 0.05‐0.63 | 0.25 | 0.10‐1.90 | 0.28 | 0.10‐0.74 | 0.34 | 0.16‐0.45 | 0.24 | 0.08‐0.94 | 0.34 | 0.17‐0.35 | .306 |
| P‐LCR (%) | 18.9‐59.2 | 34.60 | 13.7‐59.6 | 31.15 | 20.4‐63.1 | 32.60 | 18.9‐56.8 | 33.00 | 19.7‐54.7 | 31.65 | 13.0‐43.0 | .668 |
P; analyzed by Kruskal‐walis test, Mal‐ children infected with malaria parasites, Typ‐ children with salmonella infection, SCD‐ children with HbSS, Mal + Typ‐ children with malaria parasites and salmonella co‐infection, Diarrhea‐children with diarrheal diseases, Reference range; obtained from manufacturer’s [Sysmex XS–500i (Symex Corporation, Kobe, Japan)] lower and upper cut‐off values, L‐below reference range, RBC‐Red blood cell, HCT‐Hematocrit, Hb‐Hemoglobin, MCV‐Mean corpuscular volume, MCH‐Mean corpuscular hemoglobin, MCHC‐Mean cell hemoglobin concentration, RDW_CV and RDW_SD‐Red cell, distribution width, WBC‐White blood cell, LYM(%)‐Lymphocyte percentage, LYM#‐Lymphocyte number, NEUT(%)‐Neutrophil percentage, NEUT#‐Neutrophil number, MONO(%)‐Monocyte percentage, MONO#‐Monocyte number, EOS (%)‐Eosinophil percentage, EOS#‐Eosinophil number, BASO(%)‐Basophil percentage, BASO#‐Basophil number, PLT‐ Platelets, MPV‐Mean platelet volume. PDW‐Platelet distribution width, PCT‐Procalcitonin and P‐LCR‐Platelet larger cell ratio.