Table 1.
Diagnostic sensitivity and specificity, negative and positive predictive values of anti‐PGL1 IgA, IgM, and IgG tests in leprosy patients with the multibacillary (n=32) and paucibacillary (n=22) forms and in non‐endemic controls (n=17). The cut‐off values were 1.1 for IgA and 1.2 for IgG and IgM isotypes
| Anti‐PGL1 | Diagnostic Sensitivity (%) (95% CI) | Diagnostic sensitivity (%) | Diagnostic Specificity (%) | Negative predictive value (%) | Positive predictive value (%) | |
|---|---|---|---|---|---|---|
| Multibacillary form | Paucibacillary form | Multibacillary + Paucibacillary forms | ||||
| IgA | 53.1 (34.7‐70.9) | 40.9 (20.7‐63.6) | 50.0 (36.0‐64.0) | 100.0 (81.0‐100.0) | 38.7 (24.4‐54.5) | 100.0 (87.0‐100.0) |
| IgG | 21.9 (9.3‐40.0) | 22.7 (7.8‐45.4) | 22.2 (12.0‐35.6) | 100.0 (81.0‐100.0) | 28.8 (17.8‐42.1) | 100.0 (87.0‐100.0) |
| IgM | 81.3 (63.6‐92.8) | 59.1 (36.4‐79.3) | 74.1 (60.4‐85.0) | 88.2 (63.6‐98.5) | 51.7 (32.5‐70.6) | 95.2 (83.8‐99.4) |
CI, Confidence interval.