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. 2019 Oct 24;11:9095–9106. doi: 10.2147/CMAR.S219568

Figure 3.

Figure 3

Effect of SOX2 on the proliferation and stemness of UTUC cells. (A and B): SOX2-specific shRNAs significantly decreased the expression level of SOX2 in UM-UC-14 and MC-SV-HUC T2 cells. (C and D): Cell proliferation changes in UTUC cells were determined using an EdU assay. (E and F): Cell proliferation changes in UTUC cells were determined using a colony-formation assay. (G and H): The cell stemness of UTUC cells was determined using a sphere-forming assay. Cell proliferation was inhibited by silencing SOX2 in UM-UC-14 and MC-SV-HUC T2 cells. Data are shown as the mean ± SD. **p < 0.01.