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. 2019 Oct 24;11:9133–9143. doi: 10.2147/CMAR.S222716

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© 2019 Lin et al.

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EZH2 is a direct target gene of miR-214-3p. (A) The potential binding sites for miR-214-3p in the 3ʹUTR of EZH2. (B and C) Luciferase activity reporter assay was performed in HCC cells co-transfected with WT or MUT of EZH2 reporter plasmids along with miR-NC or miR-214-3p mimics. (D and E) The mRNA and protein expression levels of EZH2 in HCC cells transfected with WT or MUT of EZH2 were detected by qRT-PCR and Western blot, respectively. ***P < 0.001.