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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: Rapid Commun Mass Spectrom. 2019 Nov 15;33(21):1635–1642. doi: 10.1002/rcm.8509

Figure 4:

Figure 4:

Correlation between pyr-Val and THB-Val formation after 6 days of treosulfan therapy. The mean pyr-Val/THB-Val ratio was 1.22 with a correlation efficient of 1.35 and R2 = 0.920. Patients #07, #09, #11 and #13 (orange triangles) were excluded from the correlation analysis because they appear to have different metabolism producing significantly different pyr-Val/THB-Val (Student t-test, mean±SD 1.39±.15 vs. mean±SD 0.77±.10, p<0.0001).