Table 1.
: Baseline patient characteristics
| BASELINE CHARACTERISTICS | FMT (N = 16) | SOC (N = 32) | P-value |
|---|---|---|---|
| Mean age (years) (SD) | 62.6 (20.4) | 63.1 (19.4) | 0.93 |
| Female sex (%) | 9 (56.3%) | 18 (56.3%) | 1.00 |
| Mean BMI (kg/m2) (SD) | 24.3 (6.2) | 27.1 (7.1) | 0.20 |
| Mean CCI (SD) | 7.1 (4.3) | 7.5 (3.1) | 0.67 |
| Prior CDI (%) | 3 (18.8%) | 6 (18.8%) | 1.00 |
| Fulminant CDI (%) | 11 (68.8%) | 22 (68.8%) | 1.00 |
| History of IBD (%) | 1 (6.3%) | 0 (0%) | 0.33 |
| Immunosuppressed (%) | 5 (31.3%) | 12 (37.5%) | 0.67 |
| Mean WBC count at diagnosis (103 cells/uL) (SD) | 24.6 (19.5) | 13.2 (9.0) | *0.04 |
| Mean creatinine at diagnosis (mg/dL) (SD) | 3.0 (3.2) | 3.2 (2.4) | 0.80 |
| Mean peak WBC (103 cells/uL) (SD) | 30.6 (20.2) | 19.5 (9.9) | 0.05 |
| Mean peak creatinine (mg/dL) (SD) | 4.1 (3.7) | 4.8 (3.3) | 0.05 |
| Mean hemoglobin (g/dL) (SD) | 10.3 (1.7) | 9.3 (1.9) | 0.07 |
| Surgical history (%) | 9 (56.3%) | 15 (37.5%) | 0.54 |
| Pressors required (%) | 10 (62.5%) | 20 (62.5%) | 1.00 |
| Intubation required (%) | 10 (62.5%) | 21 (65.6%) | 0.83 |
| SBP < 100 (%) | 15 (93.8%) | 29 (90.6%) | 0.71 |
| Oral Vancomycin Received (%) | 16 (100%) | 32 (100%) | 1.00 |
| Rectal Vancomycin Received (%) | 3 (18.8%) | 3 (9.4%) | 0.36 |
| IV Metronidazole Received (%) | 12 (75.0%) | 21 (65.6%) | 0.51 |
FMT = Faecal Microbiota Transplant, SOC = Standard of Care, SD = Standard Deviation, BMI = Body Mass Index, CCI = Charlson Comorbidity Index, CDI = Clostridioides difficile infection, IBD = Inflammatory Bowel Disease, WBC = White Blood Cell, SBP = Systolic Blood Pressure, IV = intravenous