Table 1. The lipid compositions of the liposomes used in the study.
The liposomes containing phagosome mimic lipids and lipid rafts were prepared with the indicated components. The unsaturation (%) and charge (%) of the lipids were indicated. The final unsaturation (%) and charge (%) of the liposomes were calculated.
Composition (%) in liposomes | ||||||
---|---|---|---|---|---|---|
Lipid name | # of carbon and double bond in fatty acid tails | % unsaturation | Net Charge | DOPC | Phagosome mimic | Lipid Raft |
DOPC | 2x (18:1) | 100 | 0 | 100 | 0 | 0 |
POPC | 16:0-18:1 | 50 | 0 | 0 | 65 | 35 |
DPPS | 2x (16:0) | 0 | −1 | 0 | 20 | 15 |
POPE | 16:0-18:1 | 50 | 0 | 0 | 15 | 20 |
Cholesterol | NA | NA | NA | 0 | 0 | 15 |
Sphingomyelin | 2x (16:0) | 0 | 0 | 0 | 0 | 15 |
Final Unsaturation (%) | 100 | 40 | 27.5 | |||
Net Charge (%) | 0 | −20 | −15 |