Table 1.
Trends in hepatocellular carcinoma incidence rates by race/ethnicity and 10-year age group, SEER 13, 1992-2015
| Race/ethnicity | Age (y) | N | Trend 1 | Trend 2 | Trend 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Years | APC | 95% CI | Years | APC | 95% CI | Years | APC | 95% CI | |||
| Non-Hispanic white | 20-29 | 96 | -- | -- | -- | ||||||
| 30-39 | 179 | -- | -- | -- | |||||||
| 40-49 | 1,354 | 1992-98 | 19.0* | 8.3, 30.8 | 1998-09 | −0.2 | −2.4, 2.1 | 2009-15 | −12.2* | −18.9, −5.1 | |
| 50-59 | 5,897 | 1992-08 | 11.7* | 10.6, 12.8 | 2008-12 | 0.4 | −6.6, 7.9 | 2012-15 | −9.0* | −15.8, −1.6 | |
| 60-69 | 6,607 | 1992-04 | 2.5* | 1.3, 3.8 | 2004-15 | 8.7* | 7.7, 9.7 | ||||
| 70-79 | 5,434 | 1992-15 | 2.6* | 2.2, 3.0 | |||||||
| ≥80 | 2,994 | 1992-15 | 3.2* | 2.6, 3.8 | |||||||
| Non-Hispanic black | 20-29 | 34 | -- | -- | -- | ||||||
| 30-39 | 111 | -- | -- | -- | |||||||
| 40-49 | 544 | 1992-05 | 2.2 | −1.3, 5.8 | 2005-15 | −10.4* | −15.4, −5.1 | ||||
| 50-59 | 2,206 | 1992-06 | 11.2* | 9.2, 13.3 | 2006-12 | −1.2 | −5.9, 3.7 | 2012-15 | −17.2* | −26.7, −6.4 | |
| 60-69 | 2,246 | 1992-03 | 3.8* | 0.1, 7.6 | 2003-15 | 9.8* | 7.9, 11.7 | ||||
| 70-79 | 957 | 1992-15 | 2.5* | 1.6, 3.4 | |||||||
| ≥80 | 361 | 1992-15 | 1.1 | −0.7, 2.9 | |||||||
| Hispanic | 20-29 | 41 | -- | -- | -- | ||||||
| 30-39 | 102 | 1992-15 | 0.5 | −2.9, 4.0 | |||||||
| 40-49 | 904 | 1992-06 | 7.1* | 4.3, 10.0 | 2006-15 | −8.2* | −11.6, −4.6 | ||||
| 50-59 | 2,783 | 1992-05 | 8.0* | 6.3, 9.8 | 2005-12 | 3.3* | 0.4, 6.3 | 2012-15 | −12.4* | −19.4, −4.8 | |
| 60-69 | 2,742 | 1992-15 | 4.4* | 3.8, 5.1 | |||||||
| 70-79 | 1,956 | 1992-15 | 2.8* | 1.9, 3.6 | |||||||
| ≥80 | 815 | 1992-15 | 2.8* | 1.3, 4.2 | |||||||
| Asian/Pacific | 20-29 | 59 | -- | -- | -- | ||||||
| Islander | 30-39 | 322 | 1992-15 | −2.3* | −4.0, −0.6 | ||||||
| 40-49 | 1,183 | 1992-05 | 0.8 | −1.6, 3.2 | 2005-15 | −6.5* | −9.5, −3.4 | ||||
| 50-59 | 2,630 | 1992-11 | 1.4* | 0.4, 2.4 | 2011-15 | −8.3* | −15.4, −0.6 | ||||
| 60-69 | 3,384 | 1992-15 | −0.3 | −1.0, 0.5 | |||||||
| 70-79 | 3,048 | 1992-07 | 2.6* | 1.4, 3.8 | 2007-15 | −3.6* | −5.8, −1.4 | ||||
| ≥80 | 1,503 | 1992-94 | −20.2 | −57.2, 48.7 | 1994-15 | 2.2* | 1.1, 3.4 | ||||
APC, annual percent change; y, years; CI, confidence interval
-- indicates the APC could not be estimated because standard error not available and/or number of cases too small
NOTE: Each trend corresponds to the slope of the line segment between joinpoints. Asterisk denotes the APC is statistically significantly different from zero (P <0.05).