Table 1.
Clinical Characteristics at Time of Atrial Fibrillation Diagnosis, Atherosclerosis Risk in Communities (ARIC) Study
| All | No MetS | MetS | ||
|---|---|---|---|---|
| Characteristic | N=1172 | N=340 | N=832 | P-value |
| Age (Years) | 71 +/− 9 | 68.6 +/− 8 | 71.6 +/−9 | <0.0001 |
| Female sex | 514 (44) | 143 (42) | 371 (45) | 0.43 |
| Previous MI | 254 (22) | 49 (14) | 205 (25) | <0.0001 |
| Heart failure | 374 (32) | 87 (26) | 287 (35) | 0.003 |
| PAD | 125 (11) | 32 (9) | 93 (11) | 0.37 |
| Past stroke/TIA | 163 (14) | 35 (10) | 133 (16) | 0.02 |
| CHA2DS2VASc | 3.4 +/− 1.8 | 2.5 +/− 1.6 | 3.7 +/− 1.7 | <0.0001 |
| Black race | 194 (17) | 48 (14) | 146 (18) | 0.15 |
| Metabolic syndrome variables | ||||
| High waist circumference | 780 (67) | 121 (36) | 659 (79) | <0.0001 |
| High triglycerides | 624 (53) | 26 (8) | 598 (72) | <0.0001 |
| Low HDL | 704 (60) | 52 (15) | 652 (78) | <0.0001 |
| Elevated fasting plasma glucose | 795 (68) | 113 (33) | 682 (82) | <0.0001 |
| Diabetes | 351 (30) | 23 (7) | 338 (39) | <0.0001 |
| Elevated blood pressure | 955 (81) | 190 (56) | 765 (92) | <0.0001 |
| Hypertension | 819 (70) | 156 (46) | 663 (80) | <0.0001 |
*
Data are presented as n (%) or mean +/− standard deviation
§
Abbreviations: Myocardial Infarction (MI), Peripheral Arterial Disease (PAD), Transient
Ischemic Attack (TIA), High-density lipoprotein (HDL).
Elevated blood glucose - Fasting plasma glucose (FPG) ≥100 mg/dL (5.6 mmol/L) or drug treatment for elevated blood glucose and includes participants with diabetes
Elevated blood pressure - Blood pressure ≥130/85 mmHg or drug treatment for elevated blood pressure and includes participants with hypertension