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Malat1/miR-150/eIF4E signal axis regulates the Akt signaling in PDGF-BB-treated ASMCs. (A) Akt and p-Akt expression in PDGF-BB-treated ASMCs transfected with si-eIF4E, si-Malat1, miR-150 mimic, or their respective control. (B–D) The effects of GSK690693 on PDGF-BB-induced ASMC proliferation and migration determined by MTT, Transwell (scale bar: 100 μm), and western blot assays. *p < 0.05.
