Table 2.
Nucleotide variations observed between initial, WT, and recurrent, stable SCV strains.
| WT | SCV | Type of mutation | AA change | Annotation | Phenotype |
|---|---|---|---|---|---|
| C | T | intergenic | |||
| G | T | intergenic | |||
| A | G | silent | I331 | acetate kinase | |
| A | T | nonsense | Y108STOP | hypothetical protein | |
| T | C | missense | K3E | hypothetical protein | |
| ATTAGGACC | – | deletion (3aa) | rpoB | rifampicin resistance | |
| ATTCATGAG | deletion (3aa) | Alpha-beta hydrolase fold family hydrolase | |||
| CG | – | deletion 2 nt, pseudogene | rocD2 | ||
| – | CATCTG | insertion (2aa) | putative bound serine protease | ||
| A | – | deletion 1 nt, frameshift | sasA | ||
| A | – | deletion 1 nt, frameshift | glpD |