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Adverse events reported (n = 104).
| Adverse events |
All grades No. (%) |
≥Grade 3 No. (%) |
|---|---|---|
| Any | 80 (76.9) | 8 (7.7) |
| Elevated transaminases | 48 (36.2) | 5 (4.8) |
| Elevated blood creatinine | 28 (26.9) | |
| Diarrhea | 20 (19.2) | |
| Neutropenia | 20 (19.2) | 3 (2.9) |
| Edema | 18 (17.3) | |
| Leukopenia | 18 (17.3) | |
| Vision disorder | 13 (12.5) | |
| Anemia | 13 (12.5) | 1 (1.0) |
| Vomiting | 11 (10.6) | |
| Constipation | 10 (9.6) | |
| Decreased appetite | 9 (8.7) | |
| Fatigue | 7 (6.7) | |
| Dysgeusia | 5 (4.8) | |
| Nausea | 5 (4.8) | |
| Rash | 3 (2.9) | |
| Thrombocytopenia | 1 (1.0) |
